GRC 01 Sorbonne University relies on the clinical and research expertise of the structures involved in this neo-discipline that is neuro-urology, allowing the evaluation, diagnosis and medical-surgical and rehabilitative therapeutic management of ano-rectal, genito-sexual and urinary disorders observed during congenital or acquired, acute or chronic neural diseases. 

 

The research topics are:

- Bladder neurophysiology (study of perineal reflexes, bladder motor control)

- Clinical analysis of urinary, anorectal and sexual dysfunctions in neurogenic patients. 

 

The GRC 01 is the support of specific teaching Sorbonne University: neuro urology and urodynamic diploma, Master 2 Healthcare Clinical Research with a specific program (ReClip: Clinical Research in Pelvi-Perineology).  

GREEN allows to respond to institutional or non-institutional, French or international calls for tenders. 

GREEN promotes the development of industrial cooperation. 

GREEN allows to manage through Sorbonne University, specific staff dedicated to clinical research in neuro-urology. 

GREEN allows the reception of students in Masters of clinical research (mainly Master 2 ReClip (Clinical Research in Pelvi-Perineology) and by its membership to the doctoral school ED3C the reception of science theses. 

 

Research topics are in general:

clinical and experimental studies in the field of bladder neurophysiology and clinical neuro-urology; study of perineal reflexes; study of the neurological control of sphincter activity; study of the neurological control of bladder activity.

Specific research studies are:

- study of autonomic nervous system dysfunction in neurogenic disorders ;

- study of the mechanisms of bladder motor function and sensitivity in normal and pathological conditions;

- analysis of the physiological perineal reflexes and their alterations during diseases of the nervous system;

- study of bladder, anorectal and perineal sensitivity in physiological and pathological conditions;

- study of attentional and cognitive mechanisms of bladder control and the need to urinate;

- study of the pathophysiological factors of alterations of the sacral reflexes;

- analysis of the mechanisms of action and modalities of optimization of central and peripheral neuromodulations during sphincter, urinary and anorectal disorders. 

 

Finally, GREEN supports para-medical research with specific topics: analysis of the organic, psychogenic, psycho-behavioural and environmental determinants of the conditions of learning, achievement, acceptance and compliance of pelvic-perineal self-care in the neurological patient (e.g. self intermittent catherization);